E1253
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E1253
Sigma
Estriol
≥97%
| Synonym: | 1,3,5(10)-Estratriene-3,16α,17β-triol, 16α-Hydroxyestradiol, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene |
| CAS Number: | 50-27-1 |
| Linear Formula: | C18H24O3 |
| Molecular Weight: | 288.38 |
| Beilstein Registry Number: | 2508172 |
| EC Number: | 200-022-2 |
| MDL number: | MFCD00003691 |
| PubChem Substance ID: | 24894396 |
Description
| Biochem/physiol Actions | Metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and estrone are produced by the placenta during pregnancy. These are also the primary estrogens produced by adipose tissue in men and in post-menopausal women. |
Properties
| assay | ≥97% |
| mp | 280-282 °C(lit.) |
| Gene Information | human ... SERPINA6(866) |
| rat ... Ar(24208) | |
| mouse ... Esr1(13982) |
Safety
| Personal Protective Equipment | Eyeshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 60-61-40 |
| Safety Statements | 53-22-36/37/39-45 |
| WGK Germany | 3 |
| RTECS | KG8225000 |
References
| reference | Mendelson, C.R., Regulation of estrogen biosynthesis by human adipose cells in vitro. Mol. Cell. Endocrinol. 52, 169, (1987) Abstract |
| Merck | Merck 13,3742 |
| Beilstein | Beil. 6,IV,7550 |
| Corp MSDS 1 (1), 1539:D / FT-IR 2 (3), 4218:D / FT-NMR 1 (3), 565:C / RegBook 1 (2), 2853:N / Sigma FT-IR 1 (1), 1247:C / Structure Index 1, 457:B:3 |
